Ototoxicity

basic science and clinical applications

Publisher: New York Academy of Sciences in New York, N.Y

Written in English
Published: Pages: 438 Downloads: 829
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Subjects:

  • Ototoxic agents -- Congresses.,
  • Ear -- Effects of drugs on -- Congresses.,
  • Drugs -- Side effects.

Edition Notes

Includes bibliographical references and index.

Statementedited by Donald Henderson ... [et al.].
GenreCongresses.
SeriesAnnals of the New York Academy of Sciences -- v.884
ContributionsHenderson, Donald, 1938-, New York Academy of Sciences.
The Physical Object
Paginationxi, 438 p. :
Number of Pages438
ID Numbers
Open LibraryOL19123651M
ISBN 1015573312045

Ototoxicity is when a person develops hearing or balance problems due to a medicine. This can happen when someone is on a high dose of a drug that treats cancer, infections, or other illnesses. as needing time to adapt their vision when switching from reading a book to reading something at a distance; Nausea, vomiting, diarrhea, and changes. Ototoxic Hearing Loss: Signs and Treatment. Ototoxicity is literally “ear poisoning.” It comes from a combination of two latin words: Oto=Ear. Toxicity=poisoning. Ototoxicity occurs when a person ingests chemicals or certain medications that can adversely affect the way the inner ear functions. Specifically, some drugs can damage the. For a more complete list of medications, we recommend a book: Ototoxic Drugs Exposed (3rd Edition) by Neil G. Bauman, Ph. D. Or you can visit Neil Bauman, Ph.D. website by clicking here. Other Resources MERCK MANUAL - Drug-Induced Ototoxicity mcgivesback.com - Ototoxicity Other Causes of Sudden Deafness (NIDCD). Clearly, ototoxic drugs are far more common and prevalent than we realize. It’s best to not only become educated about what your doctor is prescribing you but also research options for other drugs and look for a second opinion. Toxicity to the ear is an insidious state because it can go undetected for so long.

Apr 18,  · I am not aware of another book with so much information totally focused on ototoxicity. The book opens with basics such as anatomy and physiology of the hearing and balance systems, and quickly progressing to Systemic Toxicity, Topical Toxicity, Interventions, Therapeutic Uses of Ototoxic Effects, and finally - and importantly - Medico Legal. Since most ototoxicity occurs when the harmful drugs are used in high doses, careful dose calculations are the best method of prevention. Sometimes it is possible to replace the ototoxic drugs with drugs that have less severe adverse effects. Resources BOOKS. Ototoxicity. Shlomit Yust-Katz, Mark R. Gilbert, in Abeloff's Clinical Oncology (Fifth Edition), Ototoxicity. Ototoxicity is a dose-related effect of cisplatin. Long-term ototoxicity was found to be correlated to serum platinum levels. Patients receiving more than mg/m 2 are at high risk for the development of hearing loss. Hearing loss, particularly when it is moderate to severe, often. Ototoxicity: toxicity (the state of being poisonous or damaging) to the ear. The term ototoxicity is used in medicine to refer to substances, typically medications, which are damaging to the auditory nerve or to the vestibular system of the ear. The effects of an ototoxic substance may be permanent or temporary as well as mild to severe in intensity.

Ototoxicity Download PDF EPUB FB2

Online shopping from a great selection at Books Store. Ototoxic Drugs Exposed (3rd Edition): The Shocking Truth About Prescription Drugs, Medications, Chemicals and Herbals That Can (and Do) Damage Our Ears. Ototoxicity is a compendium of information on the ototoxic Ototoxicity book of clinically useful drugs.

Each section of this thorough text is written by a leading authority in the field. The book reviews. This highly anticipated text is the only publication on pharmacology and ototoxicity written specifically for audiologists.

With contributions from leading audiologists, basic scientists, pharmacologists, and otolaryngologists, Pharmacology and Ototoxicity for Audiologists provides both basic and advanced coverage of topics critical to successful clinical mcgivesback.com by: Drug-induced ototoxicity has been known for centuries.

Already in the seventeenth century, hearing loss was described to be a side effect of quinine. The post- World War II pharmaceutical industry boomed with the production of aminoglycoside antibiotics followed by diuretics and cytostatic drugs.

Wide-spread and long-term usage of these medications brought the knowledge about their unwanted Author: Agnieszka J. Szczepek.

A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text.

Feb 26,  · Abstract Ototoxicity is the pharmacological adverse reaction affecting the inner ear or auditory nerve, characterized by cochlear or vestibular dysfunction. The panorama of drug-induced hearing loss has widened over last few mcgivesback.com by: 9.

Position Statement and Practice Guidelines American Academy of Audiology's Position Statement and Practice Guidelines on Ototoxicity Monitoring (PDF). Occupational Ototoxins (Ear Poisons) and Hearing Loss The Problem It is a well-known fact that hazardous noise exposure in the workplace can cause noise- induced hearing loss.

Occupational ototoxins have not commanded as much attention, yet pose a significant health risk to our workforce. Ototoxic chemicals either cause hearing loss. List of Ototoxic Medications.

When a medication is ototoxic, it Ototoxicity book a toxic effect on Ototoxicity book ear or its nerve supply. Depending on the medication and dosage, the effects of ototoxic medications can be temporary or permanent. The American Tinnitus Association (ATA) recognizes that the following ototoxic drugs may cause more permanent tinnitus symptoms.

Jun 12,  · Otolaryngologist and research professor  Dr. Leonard Rybak, Ph.D, M.D., explains, “Ototoxicity is the process by which the inner ear is damaged by a drug.

It can affect either the balance system or the auditory system, or sometimes both.” Ototoxicity literally means “ear poisoning” (“oto” = ear, “toxicity” = poisoning). Ototoxic antibiotics should be avoided during pregnancy, because they can damage the fetal labyrinth.

The elderly and people with preexisting hearing loss should not be treated with ototoxic drugs if other effective drugs are available.

The lowest effective dosage of ototoxic drugs should be used and levels should be closely monitored. Certain prescription drugs can, over time, have an ototoxic effect on your hearing, causing hearing loss and ear ringing from tinnitus.

Ototoxicity may be reversible or may be permanent, depending on the type of medication used, dosage and duration of treatment.

How common is ototoxicity. No one knows how many people suffer from ototoxicity each year or the percentage of vestibular disorders caused by ototoxicity. What is known is that when permanent and extensive ototoxicity occurs, the effects can take a terrible toll on a person’s ability to function.

Feb 23,  · Ototoxic synergism occurs if several ototoxic drugs are administered concurrently, potentiation of the ototoxicity is likely to occur, even when the dose of either drug is within the recommended limits.

Before prescribing any drug with ototoxic potential these group of high risk patients must be kept in mcgivesback.com by: Ototoxic Drugs Exposed (3rd edition) reveals how prescription drugs damage ears far more than anyone imagines.

In this book you will learn that some ototoxic drugs slowly and insidiously rob you of your hearing, cause your ears to ring or destroy your balance.

"This original text on ototoxicity belongs in the hands of every doctor who prescribes certain systemic or topical drugs - such as the aminoglycosides - and everyone who sees patients with ear disorders.".

Ototoxicity is of concern with most commercial otic preparations if the tympanum is ruptured and penetration into the middle ear is possible. In patients with chronic otitis externa it may be difficult to evaluate the tympanum even under general anesthesia.

mcgivesback.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started inthis collection now contains interlinked topic pages divided into a tree of 31 specialty books and chapters.

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Jul 05,  · Ototoxic substances damage the small hair cells within your ear, crucial to the sound conversion process. Ototoxicity damages your ears in three main ways.

Book your free hearing consultation today. If you think you’ve already experienced hearing loss due to ototoxicity, you should speak with a hearing healthcare professional. Ototoxicity Definition Ototoxicity is damage to the hearing or balance functions of the ear by drugs or chemicals.

Description Ototoxicity is drug or chemical damage to the inner ear. This section of the ear contains both the hearing mechanism and the vestibulocochlear nerve, the nerve that sends hearing and balance information to the brain.

Because of. Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and mcgivesback.comlty: Otorhinolaryngology.

Sep 01,  · Ototoxicity 1. OTOTOXICITY DEFINTION Ototoxicity is defined as tendency of certain substances used either systemic or topical, to cause functional impairment and cellular damage to the inner ear, especially to the end organs of cochlea and vestibular divisions of 8th cranial nerve.

Jun 24,  · Few books have been published on ototoxicity. One book is Ototoxic Drugs Exposed: Prescription Drugs and Other Chemicals That Can (and Do) Damage Our Ears. This book is the result of four years of research by Neil Bauman into approximately 1, ototoxic drugs.

Another is Ototoxicity by Peter S. Roland and John A. Rutka. Cisplatin is an effective drug used in the treatment of many cancers, yet its ototoxic potential places cancer patients, exposed to this drug, at risk of hearing loss, thus negatively impacting further on a patient’s quality of life.

It is paramount for health care practitioners managing such patients to be aware of cisplatin’s ototoxic properties and the clinical signs to identify Cited by: Jun 13,  · Any drug with the potential to cause toxic reactions to structures of the inner ear, including the cochlea, vestibule, semicircular canals, and otoliths, is considered ototoxic.

Drug-induced damage to these structures of the auditory and balance system can result in hearing loss, tinnitus, and dysequilibrium or dizziness. 'Ototoxicity is a compendium of information on the ototoxic potential of clinically useful drugs. Each section of this thorough text is written by a leading authority in the field.

The book reviews the important classes of medications known to cause ototoxicity and their mechanisms. The author’s comprehensive book, Ototoxic Drugs Exposed, describes the ototoxic (ear damaging) side effects of drugs and 29 chemicals known to trigger tinnitus, about drugs associ-ated with hearing loss and the hundreds of drugs that affect balance and cause other ototoxic side effects.

This book, as well as Dr. Bauman’s When Your Ears. Ototoxic Medications: Drugs that can cause hearing loss and tinnitus, League for the Hard of Hearing; Claussen, C.F, ().

Chemically induced or drug induced tinnitus. International Tinnitus Journal, 2, l Drug Facts & Comparisons.

() St. Louis, MO. J.B. Lippincott. Epstein, S. () What you should know about ototoxic medications. Jan 30,  · Similar Threads - Book Ototoxicity Valid Guinness Book of World Records for the Loudest Tinnitus CMIH, Jan 29,in forum: Support.

Ototoxicity, Paperback by Colon, Gregg (EDT), ISBNISBNBrand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the seller’s listing for full details. See all condition definitions- opens in a new window or tab Read moreabout the mcgivesback.com Rating: % positive.This highly anticipated text is the only publication on pharmacology and ototoxicity written specifically for audiologists.

With contributions from leading audiologists, basic scientists, pharmacologists, and otolaryngologists, Pharmacology and Ototoxicity for Audiologists provides both basic and advanced coverage of topics critical to successful clinical practice.Learn ototoxicity with free interactive flashcards.

Choose from different sets of ototoxicity flashcards on Quizlet.